Synthesis and characterization of thiochromone S,S-dioxides as new photolabile protecting groups
- 27 March 2008
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Chemical Communications
- No. 18,p. 2103-2105
- https://doi.org/10.1039/b801860j
Abstract
3-Arylthiochromone derivatives were synthesized as new photolabile protecting groups, in which the photoreactivity was switchable based on oxidation of the sulfur atom (sulfide and sulfone); the protected substrates 9,14 released the corresponding alcohols, amines or carbonxylic acids almost quantitatively under UV-light in neutral condition and the photoproduct 10 showed high fluorescence intensity.Keywords
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