Reactivation of Hepatic EPO Synthesis in Mice After PHD Loss
- 23 July 2010
- journal article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 329 (5990), 407
- https://doi.org/10.1126/science.1192811
Abstract
Stimulating erythropoietin production in the mouse liver points to a treatment for anemia caused by chronic kidney disease.Keywords
This publication has 8 references indexed in Scilit:
- A Feedback Loop Involving the Phd3 Prolyl Hydroxylase Tunes the Mammalian Hypoxic Response In VivoMolecular and Cellular Biology, 2009
- Recombinant human erythropoiesis-stimulating agents and mortality in patients with cancer: a meta-analysis of randomised trialsThe Lancet, 2009
- Oxygen Sensing by Metazoans: The Central Role of the HIF Hydroxylase PathwayMolecular Cell, 2008
- Somatic inactivation of the PHD2 prolyl hydroxylase causes polycythemia and congestive heart failureBlood, 2008
- Regulation of adult erythropoiesis by prolyl hydroxylase domain proteinsBlood, 2008
- Failure to prolyl hydroxylate hypoxia-inducible factor α phenocopies VHL inactivation in vivoThe EMBO Journal, 2006
- Mouse model for noninvasive imaging of HIF prolyl hydroxylase activity: Assessment of an oral agent that stimulates erythropoietin productionProceedings of the National Academy of Sciences of the United States of America, 2005
- Vascular tumors in livers with targeted inactivation of the von Hippel–Lindau tumor suppressorProceedings of the National Academy of Sciences of the United States of America, 2001