Atherosclerosis A Chronic Inflammatory Disease With an Autoimmune Component
Top Cited Papers
- 26 October 2018
- journal article
- editorial
- Published by Ovid Technologies (Wolters Kluwer Health) in Circulation Research
- Vol. 123 (10), 1118-1120
- https://doi.org/10.1161/CIRCRESAHA.118.313816
Abstract
Atherosclerosis is a chronic inflammatory disease of large and medium-sized arteries that causes ischemic heart disease, strokes, and peripheral vascular disease collectively called cardiovascular disease (CVD). Atherosclerosis requires elevated LDL (low-density lipoprotein) cholesterol, which can be controlled by statins and PCSK9 (proprotein convertase subtilisin/kexin type 9) inhibitors. Both effectively control LDL cholesterol and reduce major adverse cardiovascular events by approximate to 50%.(1)Keywords
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