What if Minkowski Had Been Ageusic? An Alternative Angle on Diabetes
- 30 October 1992
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 258 (5083), 766-770
- https://doi.org/10.1126/science.1439783
Abstract
Despite decades of intensive investigation, the basic pathophysiological mechanisms responsible for the metabolic derangements associated with diabetes mellitus have remained elusive. Explored here is the possibility that traditional concepts in this area might have carried the wrong emphasis. It is suggested that the phenomena of insulin resistance and hyperglycemia might be more readily understood if viewed in the context of underlying abnormalities of lipid metabolism.Keywords
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