Depot Antipsychotics in the Prophylaxis of Bipolar Affective Disorder
- 1 December 1994
- journal article
- Published by Royal College of Psychiatrists in The British Journal of Psychiatry
- Vol. 165 (6), 827-829
- https://doi.org/10.1192/bjp.165.6.827
Abstract
Background: The efficacy of depot antipsychotic drugs in the prophylaxis of bipolar affective disorder was investigated.Method: Life charts were constructed for 18 outpatients with bipolar disorder receiving prophylactic treatment with depot medication. The durations of affective episodes were compared during periods on or off medication.Results: The subjects suffered fewer relapses and spent significantly less time in hospital (P = 0.001) for treatment of manic, depressive and mixed affective illness during treatment with depot antipsychotics.Conclusions: Depot antipsychotic medication may be a useful prophylactic treatment for certain patients with bipolar affective disorder.British Journal of Psychiatry (1994), 165, 827–829Keywords
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