Control of Granulocytes and Macrophages: Molecular, Cellular, and Clinical Aspects
- 25 October 1991
- journal article
- review article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 254 (5031), 529-533
- https://doi.org/10.1126/science.1948028
Abstract
The production and functional activity of two important white blood cells, the granulocytes and macrophages, are regulated mainly by a group of glycoprotein colony-stimulating factors. The colony-stimulating factors have been mass-produced with recombinant technology and are now proving of value in preventing or suppressing infections in a variety of individuals with subnormal or defective formation of blood cells.Keywords
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