Huntingtin Spheroids and Protofibrils as Precursors in Polyglutamine Fibrilization
Open Access
- 1 October 2002
- journal article
- Published by Elsevier BV
- Vol. 277 (43), 41032-41037
- https://doi.org/10.1074/jbc.m205809200
Abstract
No abstract availableKeywords
This publication has 31 references indexed in Scilit:
- Naturally secreted oligomers of amyloid β protein potently inhibit hippocampal long-term potentiation in vivoNature, 2002
- Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseasesNature, 2002
- Kinetic Stabilization of the α-Synuclein Protofibril by a Dopamine-α-Synuclein AdductScience, 2001
- Polyglutamine aggregation behavior in vitro supports a recruitment mechanism of cytotoxicityJournal of Molecular Biology, 2001
- Targeting small Aβ oligomers: the solution to an Alzheimer's disease conundrum?Trends in Neurosciences, 2001
- Isolation of a 40-kDa Huntingtin-associated ProteinJournal of Biological Chemistry, 2001
- Nucleated Conformational Conversion and the Replication of Conformational Information by a Prion DeterminantScience, 2000
- Assembly of Aβ Amyloid Protofibrils: An in Vitro Model for a Possible Early Event in Alzheimer's DiseaseBiochemistry, 1999
- Self-assembly of polyglutamine-containing huntingtin fragments into amyloid-like fibrils: Implications for Huntington’s disease pathologyProceedings of the National Academy of Sciences of the United States of America, 1999
- Aggregation of Huntingtin in Neuronal Intranuclear Inclusions and Dystrophic Neurites in BrainScience, 1997