Efficacy and Safety of Dupilumab in Glucocorticoid-Dependent Severe Asthma
Top Cited Papers
- 28 June 2018
- journal article
- research article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 378 (26), 2475-2485
- https://doi.org/10.1056/nejmoa1804093
Abstract
Dupilumab is a fully human anti–interleukin-4 receptor α monoclonal antibody that blocks both interleukin-4 and interleukin-13 signaling. Its effectiveness in reducing oral glucocorticoid use in patients with severe asthma while maintaining asthma control is unknown.Funding Information
- Regeneron Pharmaceuticals, Inc.
- Sanofi
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