Human TRAF3 Adaptor Molecule Deficiency Leads to Impaired Toll-like Receptor 3 Response and Susceptibility to Herpes Simplex Encephalitis
Open Access
- 24 September 2010
- journal article
- research article
- Published by Elsevier BV in Immunity
- Vol. 33 (3), 400-411
- https://doi.org/10.1016/j.immuni.2010.08.014
Abstract
No abstract availableKeywords
This publication has 41 references indexed in Scilit:
- Different modes of ubiquitination of the adaptor TRAF3 selectively activate the expression of type I interferons and proinflammatory cytokinesNature Immunology, 2009
- B-cell activating factor receptor deficiency is associated with an adult-onset antibody deficiency syndrome in humansProceedings of the National Academy of Sciences of the United States of America, 2009
- Nonredundant and complementary functions of TRAF2 and TRAF3 in a ubiquitination cascade that activates NIK-dependent alternative NF-κB signalingNature Immunology, 2008
- Noncanonical NF-κB activation requires coordinated assembly of a regulatory complex of the adaptors cIAP1, cIAP2, TRAF2 and TRAF3 and the kinase NIKNature Immunology, 2008
- NIK overexpression amplifies, whereas ablation of its TRAF3-binding domain replaces BAFF:BAFF-R-mediated survival signals in B cellsProceedings of the National Academy of Sciences of the United States of America, 2008
- Frequent Engagement of the Classical and Alternative NF-κB Pathways by Diverse Genetic Abnormalities in Multiple MyelomaCancer Cell, 2007
- Promiscuous Mutations Activate the Noncanonical NF-κB Pathway in Multiple MyelomaCancer Cell, 2007
- X-linked susceptibility to mycobacteria is caused by mutations in NEMO impairing CD40-dependent IL-12 productionThe Journal of Experimental Medicine, 2006
- Critical role of TRAF3 in the Toll-like receptor-dependent and -independent antiviral responseNature, 2005
- Specificity in Toll-like receptor signalling through distinct effector functions of TRAF3 and TRAF6Nature, 2005