Oncolytic adenoviruses
Open Access
- 1 September 2012
- journal article
- Published by Taylor & Francis Ltd in OncoImmunology
- Vol. 1 (6), 979-981
- https://doi.org/10.4161/onci.20172
Abstract
The therapeutic efficacy of oncolytic viruses including adenovirus has been thought to depend mostly on direct viral destruction of tumor cells. However, this view has changed with the discovery that oncolysis can also induce innate and antigen-specific adaptive immunity against the tumor. Here we summarize our findings from cancer patients.Keywords
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