Occupational Exposure to Dibutyl Phthalate Among Manicurists
- 1 June 2008
- journal article
- Published by Ovid Technologies (Wolters Kluwer Health) in Journal of Occupational and Environmental Medicine
- Vol. 50 (6), 705-711
- https://doi.org/10.1097/jom.0b013e3181651571
Abstract
To measure manicurists' exposure to dibutyl phthalate (DBP) at work and to determine whether workplace characteristics influence this exposure. DBP is a reproductive and developmental toxicant in rats and is used in nail polish to hold color and prevent chipping. Pre- and postshift spot urine samples were collected from 40 manicurists. Linear regression compared the relationship between the log of the cross-shift differences in urinary phthalate monoester metabolite concentrations and use of workplace exposure control methods. There was a statistically significant cross-shift increase of 17.4 ng/mL in the urinary concentration of mono-n-butyl phthalate, the major metabolite of DBP. Use of gloves reduced mono-n-butyl phthalate concentrations by 15.1 ng/mL below the preshift concentration compared with a 20.5 ng/mL increase if gloves were not worn. Manicurists are occupationally exposed to DBP and glove use may minimize this exposure.Keywords
This publication has 31 references indexed in Scilit:
- Decreased Serum Free Testosterone in Workers Exposed to High Levels of Di- n -butyl Phthalate (DBP) and Di-2-ethylhexyl Phthalate (DEHP): A Cross-Sectional Study in ChinaEnvironmental Health Perspectives, 2006
- Influence of Alimentary Abstinence on Body Burden to PhthalatesEpidemiology, 2006
- Mono-(3-Carboxypropyl) Phthalate, A Metabolite of Di-n-Octyl PhthalateJournal of Toxicology and Environmental Health, Part A, 2006
- Cross-cultural perspectives on research participation and informed consentSocial Science & Medicine (1982), 2006
- Personal Care Product Use Predicts Urinary Concentrations of Some Phthalate MonoestersEnvironmental Health Perspectives, 2005
- Costs and Strategies in Minority Recruitment for Osteoporosis ResearchJournal of Bone and Mineral Research, 2003
- Assessment of the Developmental Toxicity, Metabolism, and Placental Transfer of Di-n-butyl Phthalate Administered to Pregnant RatsToxicological Sciences, 1998
- Male Reproductive Tract Malformations in Rats Following Gestational and Lactational Exposure to Di(n-butyl) Phthalate: An Antiandrogenic Mechanism?Toxicological Sciences, 1998
- INTERPRETATION OF URINE RESULTS USED TO ASSESS CHEMICAL EXPOSURE WITH EMPHASIS ON CREATININE ADJUSTMENTS: A REVIEWAihaj Journal, 1993
- The renal handling of terephthalic acidToxicology and Applied Pharmacology, 1985