Cariprazine (RGH-188), a potent D3/D2 dopamine receptor partial agonist, binds to dopamine D3 receptors in vivo and shows antipsychotic-like and procognitive effects in rodents
- 30 November 2011
- journal article
- Published by Elsevier BV in Neurochemistry International
- Vol. 59 (6), 925-935
- https://doi.org/10.1016/j.neuint.2011.07.002
Abstract
No abstract availableKeywords
This publication has 51 references indexed in Scilit:
- Current state of agonist radioligands for imaging of brain dopamine D2/D3 receptors in vivo with positron emission tomography.Current Topics in Medicinal Chemistry, 2010
- Mouse behavioral endophenotypes for schizophreniaBrain Research Bulletin, 2010
- Action of novel antipsychotics at human dopamine D3 receptors coupled to G protein and ERK1/2 activationNeuropharmacology, 2007
- Antipsychotic-Like vs Cataleptogenic Actions in Mice of Novel Antipsychotics Having D2 Antagonist and 5-HT1A Agonist PropertiesNeuropsychopharmacology, 2005
- Cholinesterase Inhibitors Ameliorate Behavioral Deficits Induced by MK-801 in MiceNeuropsychopharmacology, 2005
- Aripiprazole: A comprehensive review of its pharmacology, clinical efficacy, and tolerabilityClinical Therapeutics, 2004
- Increased baseline occupancy of D 2 receptors by dopamine in schizophreniaProceedings of the National Academy of Sciences of the United States of America, 2000
- A targeted mutation of the D3 dopamine receptor gene is associated with hyperactivity in mice.Proceedings of the National Academy of Sciences of the United States of America, 1996
- The behavioral effects of MK-801 injected into nucleus accumbens and caudate-putamen of ratsPharmacology Biochemistry and Behavior, 1995
- Effects of mecamylamine, nicotine, atropine and physostigmine on the phencyclidine-induced behavioral toxicityPharmacology Biochemistry and Behavior, 1984