A CRISPR Dropout Screen Identifies Genetic Vulnerabilities and Therapeutic Targets in Acute Myeloid Leukemia
Top Cited Papers
Open Access
- 1 October 2016
- journal article
- resource
- Published by Elsevier BV in Cell Reports
- Vol. 17 (4), 1193-1205
- https://doi.org/10.1016/j.celrep.2016.09.079
Abstract
No abstract availableKeywords
This publication has 49 references indexed in Scilit:
- Pan-cancer patterns of somatic copy number alterationNature Genetics, 2013
- The Origin and Evolution of Mutations in Acute Myeloid LeukemiaCell, 2012
- Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemiaNature, 2011
- RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemiaNature, 2011
- MLL-Rearranged Leukemia Is Dependent on Aberrant H3K79 Methylation by DOT1LCancer Cell, 2011
- The landscape of somatic copy-number alteration across human cancersNature, 2010
- Signatures of mutation and selection in the cancer genomeNature, 2010
- Agouti C57BL/6N embryonic stem cells for mouse genetic resourcesNature Methods, 2009
- A Genome-wide RNAi Screen Identifies Multiple Synthetic Lethal Interactions with the Ras OncogeneCell, 2009
- FLT3 Mutations Confer Enhanced Proliferation and Survival Properties to Multipotent Progenitors in a Murine Model of Chronic Myelomonocytic LeukemiaCancer Cell, 2007