Impact of STAT3 Phosphorylation on the Clinical Effectiveness of Anti-EGFR–Based Therapy in Patients With Metastatic Colorectal Cancer
Open Access
- 31 March 2013
- journal article
- Published by Elsevier BV in Clinical Colorectal Cancer
- Vol. 12 (1), 28-36
- https://doi.org/10.1016/j.clcc.2012.09.002
Abstract
No abstract availableKeywords
Funding Information
- “Ligue contre le cancer du Grand Est”
This publication has 34 references indexed in Scilit:
- A Multiplex SNaPshot Assay as a Rapid Method for Detecting KRAS and BRAF Mutations in Advanced Colorectal CancersThe Journal of Molecular Diagnostics, 2011
- The JAK2/STAT3 signaling pathway is required for growth of CD44+CD24– stem cell–like breast cancer cells in human tumorsJCI Insight, 2011
- Cetuximab Plus Irinotecan, Fluorouracil, and Leucovorin As First-Line Treatment for Metastatic Colorectal Cancer: Updated Analysis of Overall Survival According to Tumor KRAS and BRAF Mutation StatusJournal of Clinical Oncology, 2011
- STAT3 Expression, Molecular Features, Inflammation Patterns, and Prognosis in a Database of 724 Colorectal CancersClinical Cancer Research, 2011
- Randomized, Phase III Trial of Panitumumab With Infusional Fluorouracil, Leucovorin, and Oxaliplatin (FOLFOX4) Versus FOLFOX4 Alone As First-Line Treatment in Patients With Previously Untreated Metastatic Colorectal Cancer: The PRIME StudyJournal of Clinical Oncology, 2010
- Residual breast cancers after conventional therapy display mesenchymal as well as tumor-initiating featuresProceedings of the National Academy of Sciences of the United States of America, 2009
- K-rasMutations and Benefit from Cetuximab in Advanced Colorectal CancerNew England Journal of Medicine, 2008
- Clinical relevance of KRAS mutation detection in metastatic colorectal cancer treated by Cetuximab plus chemotherapyBritish Journal of Cancer, 2007
- The STATs of cancer — new molecular targets come of ageNature Reviews Cancer, 2004
- Constitutive Stat3 activity up-regulates VEGF expression and tumor angiogenesisOncogene, 2002