Selector for Structural Isomers of Neutral Molecules
- 2 April 2008
- journal article
- Published by American Physical Society (APS) in Physical Review Letters
- Vol. 100 (13), 133003
- https://doi.org/10.1103/physrevlett.100.133003
Abstract
We have selected and spatially separated the two conformers of 3-aminophenol () present in a molecular beam. Analogous to the separation of ions based on their mass-to-charge ratios in a quadrupole mass filter, the neutral conformers are separated based on their different mass-to-dipole-moment ratios in an ac electric quadrupole selector. For a given ac frequency, the individual conformers experience different focusing forces, resulting in different transmissions through the selector. These experiments demonstrate that conformer-selected samples of large molecules can be prepared, offering new possibilities for the study of gas-phase biomolecules.
Keywords
This publication has 30 references indexed in Scilit:
- Gas-Phase Spectroscopy of Biomolecular Building BlocksAnnual Review of Physical Chemistry, 2007
- Spectroscopically-tested, improved, semi-empirical potentials for biological molecules: Calculations for glycine, alanine and prolineElectronic supplementary information (ESI) available: Geometries (MP2 and PM3) of alanine, glycine and proline conformers I and II. See http://www.rsc.org/suppdata/cp/b3/b315326f/Physical Chemistry Chemical Physics, 2004
- Direct Measurement of Energy Thresholds to Conformational Isomerization in TryptamineScience, 2004
- Fingerprint IR Spectroscopy to Probe Amino Acid Conformations in the Gas PhasePhysical Review Letters, 2003
- Molecular physics of building blocks of life under isolated or defined conditionsThe European Physical Journal D, 2002
- Pairing of isolated nucleic-acid bases in the absence of the DNA backboneNature, 2000
- Conformational landscapes in amino acids: infrared and ultraviolet ion-dip spectroscopy of phenylalanine in the gas phaseChemical Physics Letters, 2000
- Bond Lengths in Free Molecules of Buckminsterfullerene, C 60 , from Gas-Phase Electron DiffractionScience, 1991
- Electronic spectrum of the amino acid tryptophan cooled in a supersonic molecular beamThe Journal of Chemical Physics, 1985
- Millimeter wave spectrum of glycine. A new conformerJournal of the American Chemical Society, 1980