Development of the human cancer microRNA network
Open Access
- 1 January 2010
- journal article
- Published by Springer Science and Business Media LLC in Silence
- Vol. 1 (1), 6-14
- https://doi.org/10.1186/1758-907x-1-6
Abstract
MicroRNAs are a class of small noncoding RNAs that are abnormally expressed in different cancer cells. Molecular signature of miRNAs in different malignancies suggests that these are not only actively involved in the pathogenesis of human cancer but also have a significant role in patients survival. The differential expression patterns of specific miRNAs in a specific cancer tissue type have been reported in hundreds of research articles. However limited attempt has been made to collate this multitude of information and obtain a global perspective of miRNA dysregulation in multiple cancer types.Keywords
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