Diffusion‐weighted magnetic resonance imaging in patients selected for radical cystectomy: detection rate of pelvic lymph node metastases
- 25 August 2011
- journal article
- Published by Wiley in BJU International
- Vol. 109 (7), 1031-1036
- https://doi.org/10.1111/j.1464-410x.2011.10446.x
Abstract
To evaluate whether DW-MRI improves the detection of pelvic lymph nodes metastates in patients with bladder cancer undergoing radical cystectomy. 36 patients with CT scan negative for nodal metastates underwent DW-MRI before surgery. Diagnostic accuracy of DW-MRI was compared with histopathological findings. Mean ADC value was 0.85 × 10(-3) mm(3)/s in the nodal metastatic group and 1 × 10(-3) mm(3)/s in the nodal non-metastatic group (P = 0.02). The ADC cut-off value, obtained by the ROC curve was 0.86 × 10(-3) mm(3)/s. Patient-based sensitivity, specificity and positive and negative predictive values were 76.4%, 89.4%, 26.6%, and 71.4%, respectively. DW-MRI may be used to differentiate metastatic from non-metastatic lymph nodes in patients with high-grade bladder cancer.Keywords
This publication has 36 references indexed in Scilit:
- Bladder cancerThe Lancet, 2009
- Molecular Positron Emission Tomography and PET/CT Imaging in Urological MalignanciesEuropean Urology, 2007
- Lymph Node Metastasis in Bladder CancerEuropean Urology, 2006
- Lymphoscintigraphic sentinel node identification in patients with breast cancer: the role of SPECT-CTEuropean Journal of Nuclear Medicine and Molecular Imaging, 2005
- Urinary Bladder Cancer: Preoperative Nodal Staging with Ferumoxtran-10–enhanced MR ImagingRadiology, 2004
- PROSPECTIVELY PACKAGED LYMPH NODE DISSECTIONS WITH RADICAL CYSTECTOMY: EVALUATION OF NODE COUNT VARIABILITY AND NODE MAPPINGJournal of Urology, 2004
- NODAL INVOLVEMENT IN BLADDER CANCER CASES TREATED WITH RADICAL CYSTECTOMY: INCIDENCE AND PROGNOSISJournal of Urology, 2004
- Stage Specific Lymph Node Metastasis Mapping in Radical Cystectomy SpecimensJournal of Urology, 2004
- Extended Radical Lymphadenectomy in Patients With Urothelial Bladder Cancer:: Results of a Prospective Multicenter StudyJournal of Urology, 2004
- LIMITATIONS OF COMPUTERIZED TOMOGRAPHY IN STAGING INVASIVE BLADDER CANCER BEFORE RADICAL CYSTECTOMYJournal of Urology, 2000