Establishment of robust functional assays for the characterization of neuropeptide Y (NPY) receptors: identification of 3-(5-benzoyl-thiazol-2-ylamino)-benzonitrile as selective NPY type 5 receptor antagonist
- 30 June 2005
- journal article
- research article
- Published by Elsevier BV in Neuropharmacology
- Vol. 48 (7), 1043-1055
- https://doi.org/10.1016/j.neuropharm.2005.01.020
Abstract
No abstract availableKeywords
This publication has 31 references indexed in Scilit:
- G-Protein Coupled Receptors as Allosteric MachinesReceptors and Channels, 2004
- The [35S]GTPγS binding assay: approaches and applications in pharmacologyLife Sciences, 2003
- Neuropeptide systems as novel therapeutic targets for depression and anxiety disordersTrends in Pharmacological Sciences, 2003
- Evaluation of FLIPR Calcium 3 Assay Kit—A New No-Wash Fluorescence Calcium Indicator ReagentSLAS Discovery, 2003
- Novel Hexahydrospiro[piperidine-4,1‘-pyrrolo[3,4-c]pyrroles]: Highly Selective Small-Molecule Nociceptin/Orphanin FQ Receptor AgonistsJournal of Medicinal Chemistry, 2002
- The role of NPY in metabolic homeostasis: implications for obesity therapyExpert Opinion on Investigational Drugs, 2000
- L-152,804: Orally Active and Selective Neuropeptide Y Y5 Receptor AntagonistBiochemical and Biophysical Research Communications, 2000
- Y-receptor subtypes—how many more?Trends in Neurosciences, 1997
- Modified, cyclic dodecapeptide analog of neuropeptide Y is the smallest full agonist at the human Y2 receptorFEBS Letters, 1996
- Substitution of three amino acids switches receptor specificity of Gqα to that of GiαNature, 1993