A genomic view of the NOD-like receptor family in teleost fish: identification of a novel NLR subfamily in zebrafish
Open Access
- 1 January 2008
- journal article
- Published by Springer Science and Business Media LLC in BMC Evolutionary Biology
- Vol. 8 (1), 42
- https://doi.org/10.1186/1471-2148-8-42
Abstract
A large multigene family of NOD-like receptor (NLR) molecules have been described in mammals and implicated in immunity and apoptosis. Little information, however, exists concerning this gene family in non-mammalian taxa. This current study, therefore, provides an in-depth investigation of this gene family in lower vertebrates including extensive phylogenetic comparison of zebrafish NLRs with orthologs in tetrapods, and analysis of their tissue-specific expression.Keywords
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