Stille Cross-Couplings of Unactivated Secondary Alkyl Halides Using Monoorganotin Reagents
- 23 December 2004
- journal article
- Published by American Chemical Society (ACS) in Journal of the American Chemical Society
- Vol. 127 (2), 510-511
- https://doi.org/10.1021/ja0436300
Abstract
The first catalyst that achieves Stille cross-couplings of secondary (as well as primary) alkyl halides has been developed. The method employs easily handled and inexpensive catalyst components (NiCl2 and 2,2‘-bipyridine) and, through the use of monoorganotin reagents, avoids the formation of toxic and difficult-to-remove triorganotin side products.Keywords
This publication has 4 references indexed in Scilit:
- Total Synthesis of Anti-HIV Agent Chloropeptin IJournal of the American Chemical Society, 2003
- Synthesis of perhydro-furo[2,3-b]pyran (and furan)-3-yl methanols by oxygenative radical cyclizationTetrahedron, 1998
- New methods for reductive free-radical cyclizations of α-bromoacetals to 2-alkoxytetrahydrofurans with activated chromium(II)-acetateTetrahedron, 1993
- Structure dependence of ammonia adsorption on alkali halide clustersJournal of the American Chemical Society, 1992