Are There Predictive Factors for Long-Term Outcome after Withdrawal in Drug-Induced Chronic Daily Headache?
- 1 July 2001
- journal article
- research article
- Published by SAGE Publications in Cephalalgia
- Vol. 21 (6), 691-696
- https://doi.org/10.1046/j.1468-2982.2001.00231.x
Abstract
Objectives: To investigate prognostic factors for long-term outcome of patients after inpatient withdrawal because of drug-induced chronic daily headache. Procedures: Fifty-five patients (36 females) were re-examined by means of a standardized interview after inpatient withdrawal. The mean observation period was 9.28 ± 2.85 years (mean ± sd; median 8.58; range 5.00–13.50). Results: Five years after withdrawal, one-third of the patients (34.6%) had an overall favourable outcome, one-third (32.7%) had no recurrent drug overuse and reported a clear-cut improvement of headache, and one-third (32.7%) developed recurrent drug overuse. Most relapses occurred within 2 years, and a small percentage within 5 years. No predictors for long-term outcome after inpatient withdrawal were found. Conclusions: All patients with drug-induced chronic daily headache should be considered as good candidates for inpatient withdrawal, and no patient should be excluded from that therapy.Keywords
This publication has 19 references indexed in Scilit:
- Medikamentenindizierter KopfschmerzDer Schmerz, 1999
- Chronic tension-type headache: where are we?Brain, 1999
- Drug-Induced Headache: Long-Term Results of Stationary Versus Ambulatory Withdrawal TherapyCephalalgia, 1999
- DRUG-INDUCED HEADACHENeurologic Clinics, 1998
- Burden of migraineNeurology, 1997
- MMPI and Critical Flicker Frequency (CFF) Analysis in Headache Patients With and Without Drug AbuseHeadache: The Journal of Head and Face Pain, 1995
- Tension‐type and chronic daily headacheNeurology, 1993
- Longterm Prognosis of Analgesic Withdrawal in Patients with Drug‐Induced HeadachesHeadache: The Journal of Head and Face Pain, 1989
- Flunarizine in Prophylaxis of Childhood Migraine: A Double-Blind, Placebo-Controlled, Crossover StudyCephalalgia, 1988
- Ergotamine Abuse. Do Patients Benefit from Withdrawal?Cephalalgia, 1981