Supplementary Figures 1-4,Table S1 from Paracrine Placental Growth Factor Signaling in Response to Ionizing Radiation Is p53-Dependent and Contributes to Radioresistance

Abstract

Supplementary Data supporting results of main manuscript; with other cell lines; with control experiments; includes data table Figure S1. PlGF secretion is increased in multiple cell lines after irradiation. Figure S2. PlGF mRNA expression is increased in response to IR. Figure S3. P53 is a major regulator of PlGF in response to IR. Figure S4. Generation of PlGF knockout cell lines using CRISPR/Cas9 system. Table S1. Correlation of genetic background to tumor cell lines to early PlGF expression in response to IR.