Dysplastic naevus vs. in situ melanoma: digital dermoscopy analysis
- 1 April 2005
- journal article
- Published by Oxford University Press (OUP) in British Journal of Dermatology
- Vol. 152 (4), 679-684
- https://doi.org/10.1111/j.1365-2133.2005.06481.x
Abstract
BACKGROUND: To date, much confusion exists about the biological significance of dysplastic naevi and about the relationship between melanocytic dysplasia and clinical atypia.\ud \ud OBJECTIVES: To use a digital dermoscopy analyser with a series of 'borderline' pigmented skin lesions (i.e. dysplastic naevi and in situ melanomas) to find correlation between the studied variables and to determine their discriminating power with respect to histological diagnosis.\ud \ud METHODS: The pigmented skin lesions (n = 174) were histologically examined by three experienced dermatopathologists and identified as in situ melanomas (n = 38) and dysplastic naevi (n = 136). The system evaluated 48 parameters as possible discriminant variables, grouped into four categories: geometry, colours, textures and islands of colour. Once the lesions were analysed (stepwise discriminant analysis), sensitivity, specificity and accuracy were calculated.\ud \ud RESULTS: At the end of the stepwise procedure the percentage of cases classified correctly was 71.8%. Of 136 dysplastic naevi only 98 were classified correctly, while 27 of 38 in situ melanomas were recognized correctly.\ud \ud CONCLUSIONS: We conclude that there are so far no digital dermoscopic criteria that can clearly distinguish dysplastic naevi from in situ melanomasKeywords
This publication has 30 references indexed in Scilit:
- Case 7-2004New England Journal of Medicine, 2004
- Dysplastic NeviNew England Journal of Medicine, 2003
- Histopathologic Correlation in DermoscopyArchives of Dermatology, 2003
- The dilemma of the dysplastic nevusDermatologic Clinics, 2002
- Management of dysplastic nevi: A survey of fellows of the American Academy of DermatologyJournal of the American Academy of Dermatology, 2002
- The Precursors of Malignant MelanomaPublished by Springer Science and Business Media LLC ,2002
- Correlation between clinical atypia and histologic dysplasia in acquired melanocytic neviJournal of the American Academy of Dermatology, 2001
- Sensitivity and specificity of epiluminescence microscopy: evaluation on a sample of 2731 excised cutaneous pigmented lesionsBritish Journal of Dermatology, 2000
- EARLY DIAGNOSIS OF MALIGNANT MELANOMA BY SURFACE MICROSCOPYThe Lancet, 1987
- Intravascular papillary endothelial hyperplasia. A benign lesion mimicking angiosarcomaArchives of Dermatology, 1978