Two Active Molecular Phenotypes of the Tachykinin NK1 Receptor Revealed by G-protein Fusions and Mutagenesis
Open Access
- 1 January 2001
- journal article
- Published by Elsevier BV
- Vol. 276 (23), 19793-19799
- https://doi.org/10.1074/jbc.m100621200
Abstract
No abstract availableKeywords
This publication has 35 references indexed in Scilit:
- Kinetics of Ternary Complex Formation with Fusion Proteins Composed of the A1-Adenosine Receptor and G Protein α-SubunitsPublished by Elsevier BV ,1999
- Further Delineation of the Two Binding Sites (R*n) Associated with Tachykinin Neurokinin-1 Receptors Using [3-Prolinomethionine11]SP AnaloguesPublished by Elsevier BV ,1999
- Molecular Basis of Receptor/G-Protein-Coupling SelectivityPharmacology & Therapeutics, 1998
- Loss of activation of Gsbut not Gifollowing expression of an α2A-adrenoceptor-Gi1α fusion proteinFEBS Letters, 1998
- Measurement of agonist efficacy using an α2A‐adrenoceptor‐Gi1α fusion proteinFEBS Letters, 1997
- The dual nature of the tachykinin NK1 receptorTrends in Pharmacological Sciences, 1997
- Rescue of Functional Interactions between the α2A-Adrenoreceptor and Acylation-resistant Forms of Gi1α by Expressing the Proteins from Chimeric Open Reading FramesPublished by Elsevier BV ,1997
- Septide and neurokinin A are high‐affinity ligands on the NK‐1 receptor: evidence from homologous versus heterologous binding analysisFEBS Letters, 1996
- Involvement of Gs and Gi Proteins in Dual Coupling of the Luteinizing Hormone Receptor to Adenylyl Cyclase and Phospholipase CPublished by Elsevier BV ,1996
- Cellular signaling by an agonist-activated receptor/Gs alpha fusion protein.Proceedings of the National Academy of Sciences of the United States of America, 1994