Direct demonstration of transcriptional activation of collagen gene expression in systemic sclerosis fibroblasts: Insensitivity to TGFβ1 stimulation
- 31 August 1992
- journal article
- Published by Elsevier BV in Biochemical and Biophysical Research Communications
- Vol. 187 (1), 45-50
- https://doi.org/10.1016/s0006-291x(05)81456-1
Abstract
No abstract availableKeywords
This publication has 16 references indexed in Scilit:
- Selective upregulation of platelet-derived growth factor alpha receptors by transforming growth factor beta in scleroderma fibroblasts.The Journal of Experimental Medicine, 1992
- Fibrogenic cytokines: the role of immune mediators in the development of scar tissueImmunology Today, 1991
- The Transforming Growth Factor-beta FamilyAnnual Review of Cell Biology, 1990
- Tumor necrosis factor-alpha and interferon-gamma suppress the activation of human type I collagen gene expression by transforming growth factor-beta 1. Evidence for two distinct mechanisms of inhibition at the transcriptional and posttranscriptional levels.JCI Insight, 1990
- Peptide growth factors are multifunctionalNature, 1988
- A nuclear factor 1 binding site mediates the transcriptional activation of a type I collagen promoter by transforming growth factor-βCell, 1988
- Transforming growth factor β (TGFβ) causes a persistent increase in steady-state amounts of type I and type III collagen and fibronectin mRNAs in normal human dermal fibroblastsBiochemical Journal, 1987
- Elevated proα2(I) collagen mRNA levels in cultured scleroderma fibroblasts result from an increased transcription rate of the corresponding geneFEBS Letters, 1987
- Increased type I collagen mRNA levels in cultured scleroderma fibroblastsBiochimica et Biophysica Acta (BBA) - Gene Structure and Expression, 1984
- Increased Collagen Synthesis by Scleroderma Skin Fibroblasts In Vitro A POSSIBLE DEFECT IN THE REGULATION OR ACTIVATION OF THE SCLERODERMA FIBROBLASTJCI Insight, 1974