Risks and Impact of Angiotensin-Converting Enzyme Inhibitors or Angiotensin-Receptor Blockers on SARS-CoV-2 Infection in Adults
- 4 August 2020
- journal article
- review article
- Published by American College of Physicians in Annals of Internal Medicine
- Vol. 173 (3), 195-203
- https://doi.org/10.7326/m20-1515
Abstract
This living systematic review summarizes current evidence regarding whether the use of angiotensin-converting enzyme inhibitors or angiotensin-receptor blockers increases risk for SARS-CoV-2 infect... Background: The role of angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin-receptor blockers (ARBs) in COVID-19 disease susceptibility, severity, and treatment is unclear. Purpose: To...Keywords
This publication has 32 references indexed in Scilit:
- Grading the strength of a body of evidence when assessing health care interventions: an EPC updateJournal of Clinical Epidemiology, 2015
- Angiotensin II Mediates Angiotensin Converting Enzyme Type 2 Internalization and Degradation Through an Angiotensin II Type I Receptor–Dependent MechanismHypertension, 2014
- Angiotensin-converting enzyme 2 (ACE2) mediates influenza H7N9 virus-induced acute lung injuryScientific Reports, 2014
- Classical Renin‐Angiotensin System in Kidney PhysiologyComprehensive Physiology, 2014
- Brain Angiotensin-Converting Enzyme Type 2 Shedding Contributes to the Development of Neurogenic HypertensionCirculation Research, 2013
- The ACE2 gene: its potential as a functional candidate for cardiovascular diseaseClinical Science, 2012
- Detection of Soluble Angiotensin-Converting Enzyme 2 in Heart Failure: Insights Into the Endogenous Counter-Regulatory Pathway of the Renin-Angiotensin-Aldosterone SystemJournal of the American College of Cardiology, 2008
- Differential effect of low-dose thiazides on the renin angiotensin system in genetically hypertensive and normotensive ratsJournal of the American Society of Hypertension, 2008
- Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirusNature, 2003
- Clinical consequences of angiotensin-converting enzyme inhibitor withdrawl in chronic heart failure: A double-blind, placebo-controlled study of quinaprilJournal of the American College of Cardiology, 1993