Platinum-Based Cytotoxic Therapy in Basal Cell Carcinoma a review of the literature
- 1 January 1996
- journal article
- review article
- Published by Taylor & Francis Ltd in Acta Oncologica
- Vol. 35 (6), 677-682
- https://doi.org/10.3109/02841869609083998
Abstract
Systemic cytotoxic therapy with platinum containing regimens has been reviewed in 53 patients with progressive disease of basal cell carcinoma. The overall response rate in 46 evaluable patients was 83% with complete remission obtained in 17 patients (37%), and partial remission in 21 patients (46%). Eight patients (17%) did not respond to platinum containing therapy. The median observation time was 26 months and the median time to progression 24 months. The median number of courses was 3 (range 2 to 12), and objective response was seen after median 2 courses (range 1 to 6). Platinum-based systemic chemotherapy, either alone or in combination with other therapeutic modalities, may be indicated as treatment of basal cell carcinoma when local therapy is inadequate, or in the rare cases with advanced lesions or metastatic disease.Keywords
This publication has 20 references indexed in Scilit:
- Salvage cisplatin and adriamycin for advanced or recurrent basal or squamous cell carcinoma of the faceAnti-Cancer Drugs, 1992
- Cisplatin chemotherapy for basal cell carcinoma: The need for posttreatment biopsy—report of a caseJournal of the American Academy of Dermatology, 1990
- Systemic cytotoxic therapy of basal cell carcinoma: A review of the literatureEuropean Journal of Cancer and Clinical Oncology, 1990
- Basal cell carcinoma: Response to systemic chemotherapy for lung carcinomaJournal of the American Academy of Dermatology, 1988
- Chemotherapy of Basal Cell and Squamous Cell Carcinoma of the Eyelids and Periorbital TissuesOphthalmology, 1986
- Cisplatin and doxorubicin. An effective chemotherapy combination in the treatment of advanced basal cell and squamous carcinoma of the skinCancer, 1985
- SUCCESSFUL SYSTEMIC CHEMOTHERAPY OF ADVANCED SQUAMOUS AND BASAL CELL CARCINOMA OF THE SKIN WITH CIS-DIAMMINEDICHLOROPLATINUM III AND DOXORUBICINThe Laryngoscope, 1982
- Metastatic Basal‐Cell CarcinomaThe Journal of Dermatologic Surgery and Oncology, 1982
- Metastatic basal cell carcinomaJournal of Surgical Oncology, 1980
- Metastatic basal cell carcinoma: Review, report of a case, and chemotherapyCancer, 1974