Efficacy and Metabolic Effects of Metformin and Troglitazone in Type II Diabetes Mellitus
- 26 March 1998
- journal article
- clinical trial
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 338 (13), 867-873
- https://doi.org/10.1056/nejm199803263381303
Abstract
Combination therapy is logical for patients with non-insulin-dependent (type II) diabetes mellitus, because they often have poor responses to single-drug therapy. We studied the efficacy and physiologic effects of metformin and troglitazone alone and in combination in patients with type II diabetes.Keywords
This publication has 24 references indexed in Scilit:
- Effects of metformin on the pathways of glucose utilization after oral glucose in non—insulin-dependent diabetes mellitus patientsMetabolism, 1997
- Metabolic effects of troglitazone in the Goto-Kakizaki rat, a non-obese and normolipidemic rodent model of non-insulin-dependent diabetes mellitusMetabolism, 1997
- Mechanisms of the Glycaemic Effects of SulfonylureasHormone and Metabolic Research, 1996
- Metabolic Effects of Metformin in Non-Insulin-Dependent Diabetes MellitusNew England Journal of Medicine, 1995
- Efficacy of Metformin in Patients with Non-Insulin-Dependent Diabetes MellitusNew England Journal of Medicine, 1995
- Therapeutic Comparison of Metformin and Sulfonylurea, Alone and in Various Combinations: A double-blind controlled studyDiabetes Care, 1994
- α‐Glucosidase inhibitors in diabetes: efficacy in NIDDM subjectsEuropean Journal of Clinical Investigation, 1994
- Metabolic Effects of New Oral Hypoglycemic Agent CS-045 in NIDDM SubjectsDiabetes Care, 1992
- Double-Blind Evaluation of Efficacy and Tolerability of Metformin in NIDDMDiabetes Care, 1991
- The Triumvirate: β-Cell, Muscle, Liver: A Collusion Responsible for NIDDMDiabetes, 1988