Serum Albumin Beads: An Injectable, Biodegradable System for the Sustained Release of Drugs
- 10 July 1981
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 213 (4504), 233-235
- https://doi.org/10.1126/science.6787705
Abstract
Biologically active compounds were entrapped in cross-linked serum albumin microbeads. Injection of these drug-impregnated beads into rabbits produced no adverse immunological reactions. Sustained release (20 days) of progesterone was demonstrated in vivo.Keywords
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