Prophylactic effects of wormwood on lipid peroxidation in an animal model of lead intoxication
Open Access
- 1 January 2008
- journal article
- research article
- Published by Medknow in Indian Journal of Nephrology
- Vol. 18 (2), 51-57
- https://doi.org/10.4103/0971-4065.42333
Abstract
The ability of Wormwood ( Artemisia absinthium L.) extract (A.Ab) to restore membrane-bound enzymes like Na+-K+-ATPase, Ca++-ATPase, Mg++-ATPase, and oxidative damage induced by lead were investigated. Rats were exposed to lead acetate (750 ppm) for 11-weeks and treated during 4-weeks with A.Ab. Lipid levels, ATPase activity, thiobarbituric acid reactive substances (TBARS), and proteins carbonyl were estimated. In liver and kidney, lead acetate inhibited membrane-bound enzymes and increased ( PKeywords
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