Phosphorylation of troponin T by casein kinase TS
- 15 May 1981
- journal article
- Published by Elsevier BV in Biochemical and Biophysical Research Communications
- Vol. 100 (1), 449-454
- https://doi.org/10.1016/s0006-291x(81)80117-9
Abstract
Casein kinase TS (Ck-TS), a protein kinase ubiquitous in mammalian tissues, whose natural substrates are still unknown, can phosphorylate in vitro Troponin T-even more efficiently than casein fractions. The phosphorylation site corresponds to the acetylated N terminal seryl residue which is also phosphorylated in native Troponin T and which actually fulfils the structural requirements of Ck-TS as evidenced with model substrates. It is conceivable therefore that Troponin T might be comprised among the physiological targets of Ck-TS.Keywords
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