Choice Behavior in Rhesus Monkeys: Cocaine Versus Food
- 11 August 1978
- journal article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 201 (4355), 534-535
- https://doi.org/10.1126/science.96531
Abstract
Rhesus monkeys were allowed to choose between intravenous injections of cocaine and food reinforcement for lever pressing. A choice trial was available every 15 minutes continuously for 8 days. The animals chose cocaine almost exclusively, which resulted in high cocaine intake, decreased food intake, weight loss, and marked behavioral toxicity. The study provides evidence of the reinforcing efficacy of cocaine.Keywords
This publication has 7 references indexed in Scilit:
- Cardiovascular and Subjective Effects of Intravenous Cocaine Administration in HumansArchives of General Psychiatry, 1976
- Self-administration of psychomotor stimulant drugs: The effects of unlimited accessPharmacology Biochemistry and Behavior, 1976
- Cocaine: History, Epidemiology, Human Pharmacology, and Treatment. A Perspective on a New Debut for an Old GirlClinical Toxicology, 1975
- Tolerance development to chronic methamphetamine intoxication in the Rhesus monkeyPharmacology Biochemistry and Behavior, 1974
- Self-administration of psychoactive substances by the monkeyPsychopharmacology, 1969
- Regulation of the inspired oxygen concentration during artificial ventilationPublished by American Medical Association (AMA) ,1967
- Effects of the availability of rewarding septal and hypothalamic stimulation on bar pressing for food under conditions of deprivation.Journal of Comparative and Physiological Psychology, 1965