The Landry–Guillain–Barré Syndrome

Abstract

SINCE the original descriptions of the Landry–Guillain–Barré syndrome, first by Landry,¹ in 1859, as a brief illness characterized by rapidly spreading paralysis with minimal sensory symptoms and little or no increase of the protein in the spinal fluid, and then by Guillain, Barré and Strohl,² in 1916, and by Guillain,³ in 1936, as a syndrome of paralysis of the peripheral muscles that pursued a benign course ending in recovery and characterized by an increase of protein in the spinal fluid to 1 to 2 gm. per 100 ml., with no pleocytosis, great debate and controversy have revolved around the criteria . . .