High-Energy Shockwaves and Extracorporeal High-Intensity Focused Ultrasound
- 1 October 2003
- journal article
- review article
- Published by Mary Ann Liebert Inc in Journal of Endourology
- Vol. 17 (8), 667-672
- https://doi.org/10.1089/089277903322518680
Abstract
We review the physical interactions of focused ultrasound with tissue, describe technical features of current high-energy shockwave (HESW) and extracorporeal high-intensity focused ultrasound (HIFU) devices, and summarize the experimental and human data available to date. Tissue destruction by extracorporeal HIFU is not new: the first clinical attempts were made almost half a century ago for ablating brain tissue. Despite recent progress in the knowledge of the interactions between HIFU and tissue and significant device modifications, this technique is still in its infancy. The most promising targets for this kind of therapy in the field of urology are the kidney, bladder, and testis. The largest clinical experience with HIFU therapy currently available is for benign prostatic enlargement and prostate cancer using transrectal HIFU devices, which are not the topic of this summary. In parallel with HIFU, HESW therapy has been tested in numerous experimental and preclinical settings. This technique is currently not in routine clinical use. Theoretically, in parallel with HIFU, any organ accessible to conventional diagnostic ultrasound examination is a potential target for this kind of therapy.Keywords
This publication has 59 references indexed in Scilit:
- Magnetic Resonance Imaging-guided Focused Ultrasound SynovectomyScandinavian Journal of Rheumatology, 1999
- Regulation of heat shock protein 27 expression of prostatic cells in response to heat treatmentThe Prostate, 1998
- The combined effects of high-energy shock waves and ionising radiation on a human bladder cancer cell lineJapanese Journal of Clinical Oncology, 1996
- Treatment of Human Renal Cell Carcinoma with High-Energy Shock Waves–A New in vivo/in vitro ModelUrologia Internationalis, 1995
- High-energy shock waves pyrotherapy. A new concept in extracorporeal tumour therapySurgical Oncology, 1993
- Extracorporeal Liver Ablation Using Sonography-Guided High-Intensity Focused UltrasoundInvestigative Radiology, 1992
- Focused Extracorporeal Pyrotherapy: Feasibility Study in ManJournal of Endourology, 1992
- The cytocidal effect of high energy shock waves on human prostatic tumour cell linesEuropean Journal of Cancer and Clinical Oncology, 1989
- Evaluation of high-intensity therapeutic ultrasound irradiation in the treatment of experimental hepatomaJournal of Pediatric Surgery, 1989
- Early Experiences with Ultrasonic Irradiation of the Pallidofugal and Nigral Complexes in Hyperkinetic and Hypertonic DisordersJournal of Neurosurgery, 1959