Conducting polymers in biomedical engineering
Top Cited Papers
- 11 June 2007
- journal article
- review article
- Published by Elsevier BV in Progress in Polymer Science
- Vol. 32 (8-9), 876-921
- https://doi.org/10.1016/j.progpolymsci.2007.05.012
Abstract
Conducting polymers (CPs) were first produced in the mid-1970s as a novel generation of organic materials that have both electrical and optical properties similar to those of metals and inorganic semiconductors, but which also exhibit the attractive properties associated with conventional polymers, such as ease of synthesis and flexibility in processing. The fact that several tissues are responsive to electrical fields and stimuli has made CPs attractive for a number of biological and medical applications. This review provides information on desirable CP properties specific to biomedical applications and how CPs have been optimized to generate these properties. The manuscript first introduces different types of CPs, their unique properties and their synthesis. Then specific information is provided on their modification for use in applications such as biosensors, tissue engineering, and neural probes. Although there remain many unanswered questions, particularly regarding the mechanisms by which electrical conduction through CPs affects cells, there is already compelling evidence to demonstrate the significant impact that CPs are starting to make in the biomedical field.Keywords
This publication has 200 references indexed in Scilit:
- Micropatterned Polypyrrole: A Combination of Electrical and Topographical Characteristics for the Stimulation of CellsAdvanced Functional Materials, 2007
- Immobilization of GOD on electrochemically synthesized Ppy–PVS composite film by cross-linking via glutaraldehyde for determination of glucoseReactive and Functional Polymers, 2006
- Polymerization of the conducting polymer poly(3,4-ethylenedioxythiophene) (PEDOT) around living neural cellsBiomaterials, 2006
- Nerve growth factor‐immobilized polypyrrole: Bioactive electrically conducting polymer for enhanced neurite extensionJournal of Biomedical Materials Research Part A, 2006
- Synthesis and characterization of semiconducting polypyrrole/polyacrylamide microparticles with GOx for biosensor applicationsColloids and Surfaces A: Physicochemical and Engineering Aspects, 2005
- Overoxidized polypyrrole film directed DNA immobilization for construction of electrochemical micro-biosensors and simultaneous determination of serotonin and dopamineAnalytica Chimica Acta, 2005
- Synthesis and Electrochemical Characterization of a New Electropolymerizable Hydrophilic Viologen Designed for Enzyme WiringMicrochimica Acta, 2003
- Simple, Three‐Dimensional Microfabrication of Electrodeposited StructuresAngewandte Chemie-International Edition, 2003
- Mechanism of electromechanical actuation in polypyrroleSynthetic Metals, 1995
- ?Bananatrode? ? An electrochemical biosensor for dompamineBiotechnology Letters, 1985