The persistence of papovavirus BK DNA sequences in normal human renal tissue
- 1 January 1981
- journal article
- research article
- Published by Wiley in Journal of Medical Virology
- Vol. 8 (2), 143-150
- https://doi.org/10.1002/jmv.1890080208
Abstract
Evidence has accumulated indicating that BK virus, following an inapparent primary infection, persists in the renal organs of normal healthy individuals and reactivates upon immunosuppression. Data to support this hypothesis are presented and suggest that BK virus DNA sequences are present at very low levels in the kidneys of more than 50% of the population and that this persistence is localized in several foci within these organs.Keywords
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