Enantioselective Synthesis of Cyclic Enol Ethers and All-Carbon Quaternary Stereogenic Centers Through Catalytic Asymmetric Ring-Closing Metathesis
- 24 March 2006
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of the American Chemical Society
- Vol. 128 (15), 5153-5157
- https://doi.org/10.1021/ja058428r
Abstract
The first examples of catalytic asymmetric ring-closing metathesis (ARCM) reactions of enol ethers are reported. To identify the most effective catalysts, various chiral Mo- and Ru-based catalysts were screened. Although chiral Ru catalysts (those that do not bear a phosphine ligand) promote ARCM in some cases, such transformations proceed in 98%).This publication has 8 references indexed in Scilit:
- A Readily Available Chiral Ag-Based N-Heterocyclic Carbene Complex for Use in Efficient and Highly Enantioselective Ru-Catalyzed Olefin Metathesis and Cu-Catalyzed Allylic Alkylation ReactionsJournal of the American Chemical Society, 2005
- Chiral, Porous, Hybrid Solids for Highly Enantioselective Heterogeneous Asymmetric Hydrogenation of β‐Keto EstersAngewandte Chemie, 2003
- Synthesis of Allyl and Alkyl Vinyl Ethers Using an in Situ Prepared Air-Stable Palladium Catalyst. Efficient Transfer Vinylation of Primary, Secondary, and Tertiary AlcoholsThe Journal of Organic Chemistry, 2003
- Metathesis of Electron-Rich Olefins: Structure and Reactivity of Electron-Rich Carbene ComplexesOrganometallics, 2002
- Catalytic Asymmetric Olefin MetathesisChemistry – A European Journal, 2001
- Efficient and Recyclable Monomeric and Dendritic Ru-Based Metathesis CatalystsJournal of the American Chemical Society, 2000
- Synthesis and Activity of a New Generation of Ruthenium-Based Olefin Metathesis Catalysts Coordinated with 1,3-Dimesityl-4,5-dihydroimidazol-2-ylidene LigandsOrganic Letters, 1999
- A Recyclable Ru-Based Metathesis CatalystJournal of the American Chemical Society, 1999