Microwave-assisted synthesis in aqueous medium of new quinazoline derivatives as anticancer agent precursors
- 19 November 2008
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Green Chemistry
- Vol. 11 (2), 201-208
- https://doi.org/10.1039/b816723k
Abstract
Fast and eco-friendly microwave-irradiated reactions permitting the “green synthesis” of new 2-substituted quinazoline derivatives in aqueous medium via S-alkylation or SRN1 reaction from 2-chloromethyl-3-methylquinazolin-4(3H)-one derivatives with different benzenesulfinic acids and nitronate anions, are reported herein.Keywords
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