Mutations Which Impede Loop/Sheet Polymerization Enhance the Secretion of Human α1-Antitrypsin Deficiency Variants
Open Access
- 1 April 1995
- journal article
- Published by Elsevier BV
- Vol. 270 (15), 8393-8396
- https://doi.org/10.1074/jbc.270.15.8393
Abstract
No abstract availableKeywords
This publication has 24 references indexed in Scilit:
- Biological implications of a 3 å structure of dimeric antithrombinStructure, 1994
- The intact and cleaved human antithrombin III complex as a model for serpin–proteinase interactionsNature Structural & Molecular Biology, 1994
- Effect of the Z mutation on the physical and inhibitory properties of .alpha.1-antitrypsinBiochemistry, 1993
- The mechanism of Z α1-antitrypsin accumulation in the liverNature, 1992
- Serpin tertiary structure transformationJournal of Molecular Biology, 1991
- A general method for rapid site-directed mutagenesis using the polymerase chain reactionGene, 1990
- Disruption of the Lys‐290‐Glu‐342 salt bridge in human α1‐antitrypsin does not prevent its synthesis and secretionFEBS Letters, 1987
- Cell-specific expression of a transfected human α1-antitrypsin geneCell, 1985
- Amino acid substitution Glu→Lys in α1‐antitrypsin PiZFEBS Letters, 1976
- Purification and Partial Characterization of PAS-Positive Inclusion Bodies from the Liver in Alpha1-Antitrypsin DeficiencyNew England Journal of Medicine, 1975