Impact of Age and Medical Comorbidity on the Effectiveness of Implantable Cardioverter-Defibrillators for Primary Prevention
Open Access
- 1 January 2009
- journal article
- research article
- Published by Ovid Technologies (Wolters Kluwer Health) in Circulation: Cardiovascular Quality and Outcomes
- Vol. 2 (1), 16-24
- https://doi.org/10.1161/circoutcomes.108.807123
Abstract
Background— Although implantable cardioverter-defibrillators (ICDs) reduce mortality in primary prevention patients with left ventricular systolic dysfunction, recent studies have questioned their overall role in clinical practice, especially in older patients and those with major comorbid conditions.Keywords
This publication has 22 references indexed in Scilit:
- Effect of Cardiac and Noncardiac Conditions on Survival After Defibrillator ImplantationJournal of the American College of Cardiology, 2007
- Propensity Scores in Cardiovascular ResearchCirculation, 2007
- Cost-Effectiveness of a Microvolt T-Wave Alternans Screening Strategy for Implantable Cardioverter-Defibrillator Placement in the MADIT-II–Eligible PopulationJournal of the American College of Cardiology, 2006
- Prognostic Utility of Microvolt T-Wave Alternans in Risk Stratification of Patients With Ischemic CardiomyopathyJournal of the American College of Cardiology, 2006
- Mortality Reduction by Implantable Cardioverter-Defibrillators in High-Risk Patients With Heart Failure, Ischemic Heart Disease, and New-Onset Ventricular Arrhythmia: An Effectiveness StudyJournal of the American College of Cardiology, 2005
- Amiodarone or an Implantable Cardioverter–Defibrillator for Congestive Heart FailureThe New England Journal of Medicine, 2005
- Microvolt T-Wave Alternans Distinguishes Between Patients Likely and Patients Not Likely to Benefit From Implanted Cardiac Defibrillator TherapyCirculation, 2004
- Improved Survival with an Implanted Defibrillator in Patients with Coronary Disease at High Risk for Ventricular ArrhythmiaThe New England Journal of Medicine, 1996
- Reducing Bias in Observational Studies Using Subclassification on the Propensity ScoreJournal of the American Statistical Association, 1984
- The central role of the propensity score in observational studies for causal effectsBiometrika, 1983