A New Dehydrogeranylgeraniol Antioxidant from Saururus cernuus that Inhibits Intracellular Reactive Oxygen Species (ROS)-Catalyzed Oxidation within HL-60 Cells
- 30 May 2001
- journal article
- Published by American Chemical Society (ACS) in Journal of Natural Products
- Vol. 64 (6), 693-695
- https://doi.org/10.1021/np0101346
Abstract
A new triene, 12,13-dehydrogeranylgeraniol (1), was isolated from the aquatic plant Saururus cernuus and its structure determined spectroscopically. Compound 1 inhibits PMA-induced peroxide-catalyzed oxidation of 2',7'-dichlorodihydrofluorescein dye (DCFH) by reactive oxygen species (ROS) within human promyelocyctic HL-60 cells.Keywords
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