Peripheral T-cell lymphoma involving subcutaneous tissue
- 29 July 2006
- journal article
- case report
- Published by Wiley in British Journal of Dermatology
- Vol. 132 (2), 290-295
- https://doi.org/10.1111/j.1365-2133.1995.tb05030.x
Abstract
The peripheral T-cell lymphomas, presumably derived from various immunocompetent peripheral T-cell system components, form a heterogeneous group of non-Hodgkin's lymphomas. We describe two patients with peripheral T-cell lymphoma primarily involving subcutaneous tissue. They presented with multiple subcutaneous nodules. Skin biopsy specimens in both patients demonstrated a lobular subcutaneous infiltrate. The infiltrate consisted of small and medium-sized atypical lymphoid cells. Both patients had a protracted clinical course before they were diagnosed as having malignant lymphoma. We detected latent Epstein-Barr virus infection in the skin lesions of case 2. Latent Epstein-Barr virus infection might be related to the development of this variant of peripheral T-cell lymphoma.Keywords
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