Aminoglycoside-phosphotransferases APH(3′)-IV and APH(3″) synthesized by a strain of Campylobacter coli

Abstract

Campylobacter coli strain 981 of animal origin was resistant to erythromycin, tetracycline, streptomycin, kanamycin, ribostamycin, neomycin, paromomycin, livido-mycin, and butirosin. Resistance to aminoglycosides of strain 981 was mediated by phosphotransferases APH (3′) type-IV and APH (3″). C. coli 981 harboured three plasmids of 24, 34, and 40 Megadaltons respectively. None of these plasmids were transferable to Escherichia coli K-12 by conjugation.