WormBase: a comprehensive resource for nematode research
Open Access
- 12 November 2009
- journal article
- research article
- Published by Oxford University Press (OUP) in Nucleic Acids Research
- Vol. 38 (suppl_1), D463-D467
- https://doi.org/10.1093/nar/gkp952
Abstract
WormBase (http://www.wormbase.org) is a central data repository for nematode biology. Initially created as a service to the Caenorhabditis elegans research field, WormBase has evolved into a powerful research tool in its own right. In the past 2 years, we expanded WormBase to include the complete genomic sequence, gene predictions and orthology assignments from a range of related nematodes. This comparative data enrich the C. elegans data with improved gene predictions and a better understanding of gene function. In turn, they bring the wealth of experimental knowledge of C. elegans to other systems of medical and agricultural importance. Here, we describe new species and data types now available at WormBase. In addition, we detail enhancements to our curatorial pipeline and website infrastructure to accommodate new genomes and an extensive user base.Keywords
This publication has 22 references indexed in Scilit:
- Semi-automated curation of protein subcellular localization: a text mining-based approach to Gene Ontology (GO) Cellular Component curationBMC Bioinformatics, 2009
- Ensembl 2009Nucleic Acids Research, 2008
- Reactome knowledgebase of human biological pathways and processesNucleic Acids Research, 2008
- Sequence and genetic map of Meloidogyne hapla : A compact nematode genome for plant parasitismProceedings of the National Academy of Sciences of the United States of America, 2008
- The Pristionchus pacificus genome provides a unique perspective on nematode lifestyle and parasitismNature Genetics, 2008
- Genome sequence of the metazoan plant-parasitic nematode Meloidogyne incognitaNature Biotechnology, 2008
- InParanoid 6: eukaryotic ortholog clusters with inparalogsNucleic Acids Research, 2007
- Draft Genome of the Filarial Nematode ParasiteBrugia malayiScience, 2007
- Exploring the functional landscape of gene expression: directed search of large microarray compendiaBioinformatics, 2007
- The Generic Genome Browser: A Building Block for a Model Organism System DatabaseGenome Research, 2002