Viral Vectors for Gene Transfer
Open Access
- 28 November 2018
- journal article
- review article
- Published by Wiley in Current Protocols in Mouse Biology
- Vol. 8 (4), e58
- https://doi.org/10.1002/cpmo.58
Abstract
Viral vectors are a promising tool for effective delivery of genetic material into cells. They take advantage of the natural ability of a virus to deliver a genetic payload into cells while being genetically modified such that their ability to replicate is crippled or removed. Here, an updated overview of routinely used viral vectors, including adeno‐associated viruses (AAV), retroviruses/lentiviruses, and adenoviruses (Ads), is provided, as well as perspectives on their advantages and disadvantages in research and gene therapy. © 2018 by John Wiley & Sons, Inc.Keywords
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