Sustainable Practices in Medicinal Chemistry: Current State and Future Directions
- 9 May 2013
- journal article
- review article
- Published by American Chemical Society (ACS) in Journal of Medicinal Chemistry
- Vol. 56 (15), 6007-6021
- https://doi.org/10.1021/jm400250p
Abstract
The medicinal chemistry subgroup of the American Chemical Society’s Green Chemistry Institute Pharmaceutical Roundtable (ACS GCI PR) offers a perspective on the current state of environmentally sustainable practices in medicinal chemistry with the aim of sharing best practices more widely and highlighting some potential future developments.Keywords
This publication has 53 references indexed in Scilit:
- Practical and innate carbon–hydrogen functionalization of heterocyclesNature, 2012
- A New Reagent for Direct DifluoromethylationJournal of the American Chemical Society, 2012
- Safe, Convenient ortho-Claisen Thermal Rearrangement Using a Flow ReactorOrganic Process Research & Development, 2011
- Microwave-assisted benzyl mono- and dibromination in diethyl carbonate as environmentally friendly alternative to radical bromination in carbon tetrachlorideGreen Chemistry, 2011
- Cytochromes P450 as useful biocatalysts: addressing the limitationsChemical Communications, 2011
- Biocatalytic Asymmetric Synthesis of Chiral Amines from Ketones Applied to Sitagliptin ManufactureScience, 2010
- Catalytic C–H functionalization by metal carbenoid and nitrenoid insertionNature, 2008
- Optimisation of solvent replacement procedures according to economic and environmental criteriaChemical Engineering Journal, 2006
- The role of the medicinal chemist in drug discovery — then and nowNature Reviews Drug Discovery, 2004
- Solvent selection for pharmaceuticalsFluid Phase Equilibria, 2002