The impact of body mass index on later total hip arthroplasty for primary osteoarthritis: A cohort study in 1.2 million persons
- 28 February 2006
- journal article
- Published by Wiley in Arthritis & Rheumatism
- Vol. 54 (3), 802-807
- https://doi.org/10.1002/art.21659
Abstract
Objective To investigate the effects of body mass index (BMI), height, and age on the risk of later total hip arthroplasty for primary osteoarthritis (OA). Methods We matched screening data on body height and weight from 1,152,006 persons ages 18–67 years who attended a compulsory screening for tuberculosis in 1963–1975 with data from the Norwegian Arthroplasty Register for the years 1987–2003. We identified 28,425 total hip replacements because of primary OA. Results We found dose‐response associations between both height and BMI and later hip arthroplasty. The relative risk (RR) among men with a BMI ≥32 kg/m2 versus a BMI of 20.5–21.9 kg/m2 was 3.4 (95% confidence interval [95% CI] 2.9–4.0). The corresponding RR in women was 2.3 (95% CI 2.1–2.4). There was a decreasing trend in the RR with an increasing age at screening. Among men, the RR for an increase of 5 kg/m2 in the BMI was 2.1 (95% CI 1.7–2.5) when measured at age <25 years and 1.5 (95% CI 1.3–1.7) when measured at ages 55–59 years. Among women, the corresponding RR values were 1.7 (95% CI 1.5–1.9) and 1.1 (95% CI 1.1–1.2). Conclusion There was a strong dose‐response association between BMI and later total arthroplasty for OA of the hip. Being overweight entailed the highest RR among young participants, and the participants who were overweight at a young age maintained an excess RR for arthroplasty throughout the followup period.Keywords
This publication has 15 references indexed in Scilit:
- Weight Change and the Risk of Total Hip ReplacementEpidemiology, 2003
- Age and sex differences in hip joint space among asymptomatic subjects without structural change: Implications for epidemiologic studiesArthritis & Rheumatism, 2003
- Rates of weight change for black and white Americans over a twenty year periodInternational Journal of Obesity, 2003
- The costs of arthritisArthritis Care & Research, 2003
- Risk factors for total hip replacement due to primary osteoarthritis: A cohort study in 50,034 personsArthritis & Rheumatism, 2002
- Effects of Age on Validity of Self-Reported Height, Weight, and Body Mass Index: Findings from the Third National Health and Nutrition Examination Survey, 1988–1994Journal of the American Dietetic Association, 2001
- Ten-year trends in overweight and obesity among Danish men and women aged 30–60 yearsInternational Journal of Obesity, 2000
- The Norwegian Arthroplasty Register: 11 years and 73,000 arthroplastiesActa Orthopaedica, 2000
- Proportional hazards tests and diagnostics based on weighted residualsBiometrika, 1994