Identification of a Potent and Nonpeptidyl CCR3 Antagonist
- 2 March 2001
- journal article
- Published by Elsevier BV in Biochemical and Biophysical Research Communications
- Vol. 281 (3), 779-782
- https://doi.org/10.1006/bbrc.2001.4372
Abstract
No abstract availableKeywords
This publication has 19 references indexed in Scilit:
- Identification of Potent, Selective Non-peptide CC Chemokine Receptor-3 Antagonist That Inhibits Eotaxin-, Eotaxin-2-, and Monocyte Chemotactic Protein-4-induced Eosinophil MigrationPublished by Elsevier BV ,2000
- Chemokines — Chemotactic Cytokines That Mediate InflammationThe New England Journal of Medicine, 1998
- Enhanced expression of eotaxin and CCR3 mRNA and protein in atopic asthma. Association with airway hyperresponsiveness and predominant co‐localization of eotaxin mRNA to bronchial epithelial and endothelial cellsEuropean Journal of Immunology, 1997
- High expression of the chemokine receptor CCR3 in human blood basophils. Role in activation by eotaxin, MCP-4, and other chemokines.JCI Insight, 1997
- Eosinophils in allergic reactionsCurrent Opinion in Immunology, 1996
- Eosinophil recruitment to the lung in a murine model of allergic inflammation. The role of T cells, chemokines, and adhesion receptors.JCI Insight, 1996
- Cloning, expression, and characterization of the human eosinophil eotaxin receptor.The Journal of Experimental Medicine, 1996
- Cloning of the human eosinophil chemoattractant, eotaxin. Expression, receptor binding, and functional properties suggest a mechanism for the selective recruitment of eosinophils.JCI Insight, 1996
- Mechanisms and pharmacological manipulation of eosinophil accumulation in vivoTrends in Pharmacological Sciences, 1995
- Eotaxin: a potent eosinophil chemoattractant cytokine detected in a guinea pig model of allergic airways inflammation.The Journal of Experimental Medicine, 1994