Acquisition‐weighted stack of spirals for fast high‐resolution three‐dimensional ultra‐short echo time MR imaging

Abstract

Ultra-short echo time (UTE) MRI requires both short excitation (∼0.5 ms) and short acquisition delay (2-induced signal decay. These requirements currently lead to low acquisition efficiency when high resolution (2 decay, separates slice thickness from in-plane resolution to reduce the number of slice encodings, and uses spiral trajectories to accelerate in-plane data collections. T₂- and off-resonance induced slice widening and image blurring were calculated from 1.5 to 7 Tesla (T) through point spread function. Computer simulations were performed to optimize spiral interleaves and readout times. Phantom scans and in vivo experiments on human heads were implemented on a clinical 1.5T scanner (G_max = 40 mT/m, S_max = 150 T/m/s). Accounting for the limits on B₁ maximum, specific absorption rate (SAR), and the lowered amplitude of slab-select gradient, a sinc radiofrequency (RF) pulse of 0.8ms duration and 1.5 cycles was found to produce a flat slab profile. High in-plane resolution (0.86 mm) images were obtained for the human head using echo time (TE) = 0.608 ms and total shots = 720 (30 slice-encodings × 24 spirals). Compared with long-TE (10 ms) images, the ultrashort-TE AWSOS images provided clear visualization of short-T₂ tissues such as the nose cartilage, the eye optic nerve, and the brain meninges and parenchyma. Magn Reson Med 60:135–145, 2008.