Expert Judgment Assessment of the Mortality Impact of Changes in Ambient Fine Particulate Matter in the U.S.
- 27 February 2008
- journal article
- research article
- Published by American Chemical Society (ACS) in Environmental Science & Technology
- Vol. 42 (7), 2268-2274
- https://doi.org/10.1021/es0713882
Abstract
In this paper, we present findings from a multiyear expert judgment study that comprehensively characterizes uncertainty in estimates of mortality reductions associated with decreases in fine particulate matter (PM2.5) in the U.S. Appropriate characterization of uncertainty is critical because mortality-related benefits represent up to 90% of the monetized benefits reported in the Environmental Protection Agency’s (EPA’s) analyses of proposed air regulations. Numerous epidemiological and toxicological studies have evaluated the PM2.5−mortality association and investigated issues that may contribute to uncertainty in the concentration−response (C−R) function, such as exposure misclassification and potential confounding from other pollutant exposures. EPA’s current uncertainty analysis methods rely largely on standard errors in published studies. However, no one study can capture the full suite of issues that arise in quantifying the C−R relationship. Therefore, EPA has applied state-of-the-art expert judgment elicitation techniques to develop probabilistic uncertainty distributions that reflect the broader array of uncertainties in the C−R relationship. These distributions, elicited from 12 of the world’s leading experts on this issue, suggest both potentially larger central estimates of mortality reductions for decreases in long-term PM2.5 exposure in the U.S. and a wider distribution of uncertainty than currently employed in EPA analyses.Keywords
This publication has 13 references indexed in Scilit:
- Health Effects of Fine Particulate Air Pollution: Lines that ConnectJournal of the Air & Waste Management Association, 2006
- Reduction in Fine Particulate Air Pollution and MortalityAmerican Journal of Respiratory and Critical Care Medicine, 2006
- Spatial Analysis of Air Pollution and Mortality in Los AngelesEpidemiology, 2005
- Use of expert judgment in exposure assessment: Part 2. Calibration of expert judgments about personal exposures to benzeneJournal of Exposure Science & Environmental Epidemiology, 2003
- Lung Cancer, Cardiopulmonary Mortality, and Long-term Exposure to Fine Particulate Air PollutionJAMA, 2002
- Use of expert judgment in exposure assessment. Part I. Characterization of personal exposure to benzeneJournal of Exposure Science & Environmental Epidemiology, 2001
- Use of Probabilistic Expert Judgment in Uncertainty Analysis of Carcinogenic PotencyRegulatory Toxicology and Pharmacology, 1994
- An Association between Air Pollution and Mortality in Six U.S. CitiesNew England Journal of Medicine, 1993
- Expert Scientific Judgment and Cancer Risk Assessment: A Pilot Study of Pharmacokinetic DataRisk Analysis, 1988
- Technical Uncertainty in Quantitative Policy Analysis — A Sulfur Air Pollution ExampleRisk Analysis, 1984